Le nitrate de sodium est connu sous le nom de salpêtre du Chili ou du Pérou à cause de son abondance dans ces pays et pour le distinguer du salpêtre ordinaire qu’est le nitrate de potassium.
Il est largement utilisé dans l’agriculture comme engrais (son faible coût en fait une source d’azote très accessible). Dans les années 1800 et au début des années 1900, le nitrate de sodium a été utilisé dans la fabrication de la poudre à canon. Il est aujourd’hui encore utilisé dans les feux d’artifice, les carburants solides pour fusées, dans le traitement des eaux usées, et comme conservateur alimentaire (à polémique).
Autres noms
Fonction et caractéristiques
Listé comme fixateur de la couleur et conservateur au Codex alimentarius
CARACTÉRISTIQUES
Il s’agit d’une poudre incolore à blanche.
Utilisations
Ses principales applications alimentaire (du moins en Europe, ndr.) semblent être les fromages; les types Gouda. Comprit également dans ne nombreux pharmaceutiques et cosmétiques.
Utilisations détaillées
| # | Category | Category Description |
| 1 | Adhesive | General adhesives and binding agents for a variety of uses |
| 2 | Adhesive, water_based, consumer_use | Term applied when the only information the source indicates is ‘consumer’ or ‘consumer product’ ; also applied to terms that the source indicates are f |
| 3 | Agricultural | Relating to agricultural, including the raising and farming of animals and growing of crops |
| 4 | Agricultural, animal | Related to animals (but non-veterinary) e.g., animal husbandry, farming of animals/animal production, raising of animals for food or fur, animal feed, products for household pets |
| 5 | Agricultural, consumer_use | Term applied when the only information the source indicates is ‘consumer’ or ‘consumer product’ ; also applied to terms that the source indicates are f |
| 6 | Agricultural, crop | Products used on crops, or related to the growing of crops |
| 7 | Antifreezing | Antifreezing agents, or de-icing products |
| 8 | Antimicrobial | Type of pesticide used to destroy or inhibit the growth of disease-causing mechanisms, can be impregnated into clothing |
| 9 | Automotive_care | Relatived to the maintenance and repair of automobiles, products for cleaning and caring for automobiles (auto shampoo, polish/wax, undercarriage treatment, brake grease) |
| 10 | Beverage, food_service | Related to food and beverage service activities |
| 11 | Binding | Binding agents, used in paint, sand, etc |
| 12 | Binding, paint | Various types of paint for various uses, modifiers included when more information is known |
| 13 | Building_construction | Related to the building or construction process for buildings or boats (includes activities such as plumbing and electrical work, bricklaying, etc) |
| 14 | Building_construction, boats | Related to the building or repair of ships, pleasure boats, or sporting boats |
| 15 | Building_construction, brick | Bricks or related to bricklaying/masonry |
| 16 | Building_material | Materials used in the building process, such as flooring, insulation, caulk, tile, wood, glass, etc. |
| 17 | Building_material, paving | Related to cement, concrete, or asphalt materials |
| 18 | Casting_agent | Casting agents or molding compounds for plastics, sand, or metals |
| 19 | Chemical, laboratory | Modifier used for chemical, when chemical is used in a laboratory |
| 20 | Cleaning_washing | Related to all forms of cleaning/washing, including cleaning products used in the home, laundry detergents, soaps, de-greasers, spot removers, etc; mod |
| 21 | Cleaning_washing, consumer_use | Term applied when the only information the source indicates is ‘consumer’ or ‘consumer product’ ; also applied to terms that the source indicates are f |
| 22 | Cleaning_washing, detergent | Detergents with wide variety of applications; modifiers included when known |
| 23 | Cleaning_washing, enclosed | Products used in an enclosed setting, such as boiler and tank cleansing agents, and drain cleaners |
| 24 | Cleaning_washing, enclosed, consumer_use | Term applied when the only information the source indicates is ‘consumer’ or ‘consumer product’ ; also applied to terms that the source indicates are f |
| 25 | Cleaning_washing, flooring | Flooring materials (carpets, wood, vinyl flooring), or related to flooring such as wax or polish for floors |
| 26 | Cleaning_washing, toilets | Toilets, cleaning/sanitizing products for toilets |
| 27 | Colorant | Term used for colorants, dyes, or pigments; includes colorants for drugs, textiles, personal care products (cosmetics, tatoo inks, hair dye), food colorants, and inks for printing; modifiers included when application is known |
| 28 | Construction | General construction (as opposed to those things labeled building_construction); i.e. |
| 29 | Consumer_use | Term applied when the only information the source indicates is ‘consumer’ or ‘consumer product’ ; also applied to terms that the source indicates are f |
| 30 | Cooling_agent | Cooling agents, specific application unknown |
| 31 | Disinfectant | General disinfectants/sanitizing agnets, disinfectants related to drugs (modified by ‘drug’), and disinfectants used in drinking water, or animal feed (modified by ‘drinking_water’ and ‘feed’) |
| 32 | Drug | Drug product, or related to the manufacturing of drugs; modified by veterinary, animal, or pet if indicated by source |
| 33 | Drug, inactive_ingredient | Pharmaceutical related |
| 34 | Explosives | Explosives and pyrotechnics |
| 35 | Facility, food_production | Related to food production (restaurants, catering, etc) |
| 36 | Facility, fuel, automotive | Generally related to automobiles or their manufacture, used when automotive_care or automotive_component are not applicable (e.g. auto fuel, GPS units), or detailed information is not known |
| 37 | Feed, animal | Related to animals (but non-veterinary) e.g., animal husbandry, farming of animals/animal production, raising of animals for food or fur, animal feed, products for household pets |
| 38 | Fertilizer | Fertilizer for consumer or industrial use, and manufacturing of fertilizers |
| 39 | Fertilizer, consumer_use | Term applied when the only information the source indicates is ‘consumer’ or ‘consumer product’ ; also applied to terms that the source indicates are f |
| 40 | Filler | Fillers for paints, textiles, plastics, etc |
| 41 | Fishing | Related to the activity of fishing |
| 42 | Fluid_property_modulator | Includes antifoaming agents, coagulating agents, dispersion agents, emulsifiers, flotation agents, foaming agents, viscosity adjustors, etc |
| 43 | Food | Food for human consumption, does not include food additives (see food_additive); also includes manufacture of food, facilities related to food (with appropriate modifiers) |
| 44 | Food_additive | Includes spices, extracts, colorings, flavors, etc added to food for human consumption |
| 45 | Food_additive, flavor | General flavoring agents used in foods, including condiments and seasonings |
| 46 | Food_additive, meat | Related to the farming of meats (including cattle, poultry, swine), and the manufacturing of meat for human consumption |
| 47 | Food_contact | Includes food packaging, paper plates, cutlery, small appliances such as roasters, etc.; does not include facilities that manufacture food |
| 48 | Food_service | Related to food and beverage service activities |
| 49 | Forestry | Related to forestry |
| 50 | Fragrance | Fragrances or odor agents, can be used in home products (cleaners, laundry products, air fresheners) or similar industrial products; usage indicated when known; more specific modifiers included when known |
| 51 | Heat_transferring | Heat transferring agents, unknown usage or application |
| 52 | Hunting | Related to the activity of hunting |
| 53 | Industrial, adhesive, water_based | Modifier included when source indicates the product is water based |
| 54 | Industrial, cleaning_washing | Related to all forms of cleaning/washing, including cleaning products used in the home, laundry detergents, soaps, de-greasers, spot removers, etc; mod |
| 55 | Industrial_fluid | Industrial fluids such as hydraulic fluids, lubricating agents, functional fluids, etc |
| 56 | Industrial_manufacturing | |
| 57 | Inert | |
| 58 | Lubricant | Generic lubricants, lubricants for engines, brake fluids, oils, etc (does not include personal care lubricants) |
| 59 | Lubricant, automotive_care | Relatived to the maintenance and repair of automobiles, products for cleaning and caring for automobiles (auto shampoo, polish/wax, undercarriage treatment, brake grease) |
| 60 | Manufacturing | If applied entry is related to the manufacturing process for the product, widely applied, modifiers often included (if not included, no additional information is known) |
| 61 | Manufacturing, adhesive | General adhesives and binding agents for a variety of uses |
| 62 | Manufacturing, automotive | Generally related to automobiles or their manufacture, used when automotive_care or automotive_component are not applicable (e.g. auto fuel, GPS units), or detailed information is not known |
| 63 | Manufacturing, building_material | Materials used in the building process, such as flooring, insulation, caulk, tile, wood, glass, etc. |
| 64 | Manufacturing, building_material, paving | Related to cement, concrete, or asphalt materials |
| 65 | Manufacturing, building_material, wood | Wood used as a building material, wood preservatives |
| 66 | Manufacturing, chemical | General term used only when the only information known from the source is ‘chemical,’ typically related to manufacturing of chemicals, or laboratory chemicals |
| 67 | Manufacturing, electrical | Related to electrical work (such as wiring of a building), electric current insulation materials, or other electrical components |
| 68 | Manufacturing, electronics, computer | Related to computers or the manufacturing of computers |
| 69 | Manufacturing, explosives | Explosives and pyrotechnics |
| 70 | Manufacturing, export | Related to manufacturing for export (additional information unknown) |
| 71 | Manufacturing, food | Food for human consumption, does not include food additives (see food_additive); also includes manufacture of food, facilities related to food (with appropriate modifiers) |
| 72 | Manufacturing, machines | Manufacturing of or related to machinery, for production of cement or food, air/spacescraft machinery, electrical machinery, etc |
| 73 | Manufacturing, machines, beverage | Beverages for human consumption (e.g., juice, water, alcohol), or related to beverages for human consumption (e.g. |
| 74 | Manufacturing, machines, cigarettes | Chemicals in cigarettes, or tobacco related products, or related to the manufacturing of tobacco products |
| 75 | Manufacturing, machines, food | Food for human consumption, does not include food additives (see food_additive); also includes manufacture of food, facilities related to food (with appropriate modifiers) |
| 76 | Manufacturing, metals | Related to metals – manufacturing of metals, casting of metals, production of metals, surface treatment of metals, etc |
| 77 | Manufacturing, minerals | Non-metallic mineral products and their manufacture |
| 78 | Manufacturing, oil | Crude oil, crude petroleum, refined oil products, fuel oils, drilling oils |
| 79 | Manufacturing, paint | Various types of paint for various uses, modifiers included when more information is known |
| 80 | Manufacturing, paper | Related to the manufcturing of pulp or paper products, or paper products in general |
| 81 | Manufacturing, TV | Televisions and their manufacture |
| 82 | Manufacturing, plastics | Plastic products, industry for plastics, manufacturing of plastics, plastic additives (modifiers included when known) |
| 83 | Manufacturing, radio | Radios (communication device) |
| 84 | Manufacturing, raw_material | Raw materials used in a variety of products and industries (e.g. in cosmetics, chemical manufacturing, production of metals, etc); modifiers included when known to indicate what the raw materials are used for |
| 85 | Manufacturing, rubber | Rubber products (e.g. tires) and their manufacture |
| 86 | Manufacturing, textile | Textiles used for clothing or furniture upholstery, processes related to textiles (e.g. |
| 87 | Mining | Related to the mining industry, mining for coal, metals, etc |
| 88 | Mining, coal | Related to coal products, specifically related to manufacturing or mining |
| 89 | Mining, metals | Related to metals – manufacturing of metals, casting of metals, production of metals, surface treatment of metals, etc |
| 90 | Mining, uranium | Mining of uranium |
| 91 | Paint | Various types of paint for various uses, modifiers included when more information is known |
| 92 | Paint, water_based | Modifier included when source indicates the product is water based |
| 93 | Personal_care, cosmetics, lotion | Subcategory of personal care and cosmetics, lotions and moisturizers for consumer use |
| 94 | Pesticide | Substances used for preventing, destroying or mitigating pests |
| 95 | Pesticide, active_ingredient | Active ingredients in a product (often active ingredients in pesticide, if so also tagged with ‘pesticide’) |
| 96 | Pesticide, antimicrobial, active_ingredient | Active ingredients in a product (often active ingredients in pesticide, if so also tagged with ‘pesticide’) |
| 97 | Pesticide, bactericide | Type of pesticide that kills bacteria |
| 98 | Pesticide, biocide, non_agricultural | Pesticide for non agricultural use |
| 99 | Pesticide, inert_ingredient | Inert ingredients in a pesticide |
| 100 | Pesticide, pesticide_conventional | Conventional pesticide; chemical or substance developed or produced primarily or only for use as a pesticide |
| 101 | Pesticide, preservatives | Includes preservatives used in cosmetics, film, wood preserving agents, foods, etc (note food preservatives are also indicated as food_additive) |
| 102 | Photographic | Related to photography, film, photographic equipment, photographic laboraties, photochemicals, and developing of photographs |
| 103 | Polish | Car wax/polish, floor wax, general polishing agents, polish for metals, plastics, rubber, lacquers, leather, furniture, etc |
| 104 | Polish, automotive_care | Relatived to the maintenance and repair of automobiles, products for cleaning and caring for automobiles (auto shampoo, polish/wax, undercarriage treatment, brake grease) |
| 105 | Preservatives | Includes preservatives used in cosmetics, film, wood preserving agents, foods, etc (note food preservatives are also indicated as food_additive) |
| 106 | Printing | Related to the process of printing (newspapers, books media, etc), printing inks, toners, etc |
| 107 | Process_regulator | Accelerators, activators, oxidation agents, reducing agents, etc |
| 108 | Process_regulator, oxidant | Oxidizing/reducing agents, unknown application |
| 109 | Raw_material | Raw materials used in a variety of products and industries (e.g. in cosmetics, chemical manufacturing, production of metals, etc); modifiers included when known to indicate what the raw materials are used for |
| 110 | Resource_extraction, gas | Related to fracking, natural gas, industrial gases |
Toxicité
TRES TOXIQUE À éviter pour les enfants.
Les risques
Mention officielle : “A éviter aux nourrissons de moins de 3 mois”
Voir le nitrate de potassium, ou salpêtre E252. Le nitrate de sodium est -de plus- listé au nombre des carcinogènes à la NLM américaine (National Library of Medicine).
En dose élevée, les nitrates formant dans le corps des nitrites mènent à la cyanose, caractérisée par le bleuissement typique des lèvres, des muqueuses et de la peau. Le passage de l’oxygène dans les globules rouges en est diminué ce qui provoque en particulier chez les enfants une insuffisance respiratoire aiguë pouvant conduire à une mort par étouffement (terme technique : méthémoglobinémie). Dans le système digestif, le nitrite formé par le nitrate peut être transformé en nitrosamines cancérigènes. On connaît déjà ce phénomène du nitrate dans l’eau potable. Les nitrosamines peuvent aussi se former lorsqu’on cuit de la charcuterie saumurée avec du fromage.
Effets secondaires
L’ingestion de hautes doses pourrait aussi inhiber le fonctionnement de la glande thyroïde.
Les nitrates en eux-mêmes ne sont pas toxiques, mais lorsqu’ils sont ajoutés à la viande, ils se décomposent en nitrite. Le nitrite réagit ensuite avec les protéines pour produire des composés N-nitroso qui sont cancérigènes chez les animaux de laboratoire, les preuves ne sont pas concluantes quant à leur potentiel de provoquer un cancer (tel que le cancer de l’estomac) chez l’homme. Les effets du nitrate sur la santé comprennent une teinte bleuâtre sur la peau et les lèvres, une faiblesse, un pouls rapide, un manque de conscience, le coma et la mort. Les nourrissons sont beaucoup plus sensibles aux nitrates que les adultes. Une exposition à long terme à des niveaux inférieurs de nitrates entraîne une augmentation de la quantité d’urine, des dépôts d’amidon et des saignements de la rate. Le nitrate ne doit pas être utilisé chez les nourrissons de moins de 3 mois.
Suis-je concerné?
A cause de leur forte toxicité, les nitrates peuvent seulement être utilisés en combinaison avec du sel de cuisine pour saumurer la charcuterie et les saucisses et ainsi les conserver. Les sels contenant du nitrate fournissent l’arôme typique de la saumure et la couleur rouge de la charcuterie pouvant résister à la cuisson. Le E 251 et le E 252 peuvent aussi être utilisés pour la conservation de fromage à pâtes pressées cuites, pour les imitations de fromages et pour les poissons conservés. A cause des risques nommés ci-dessus, les valeurs prescrites sont très limitées (50– 250 milligrammes par kilogramme d’aliment).
RÉSIDUS AUTORISÉS (dits Critères de pureté)
Information non disponible
Dosage maximum dans les produits transformés
DJA; 0 – 3,7 mg./kg. de masse corporelle/jour.
L’EFSA européenne admet que cette DJA est dépassée par l’exposition alimentaire globale.
Il peut avoir une quantité maximales autorisées dans un aliment
CANADA
Liste des agents de conservation autorisés (Listes des additifs alimentaires autorisés) (Canada)
| Partie 1 – Agents de conservation de la catégorie 1 | |||
| Article | Colonne 1 Additifs | Colonne 2 Permis dans ou sur | Colonne 3 Limites de tolérance et autre conditions |
| P.1 | Nitrate de potassium | (1) Liant à viande pour saucisse séchée; saucisse semi-séchée; viande conservée et sous-produits de viande conservés, préparés selon des méthodes de salaison lente (Titre 14) | (1) Si le liant à viande est utilisé selon le mode d’emploi donné sur l’étiquette, que le nitrate de potassium soit ajouté seul ou avec du nitrate de sodium, la quantité totale de tels nitrates ainsi ajoutée à chaque lot de saucisse séchée, de saucisse semi-séchée, de viande conditionnée ou conservée, ou de sous-produits de viande conditionnée ou conservée ne doit pas excéder 0,32 once par 100 livres ou 200 parties par million, calculée avant que le produit ne soit fumé, cuit ou fermenté. Si le nitrate de potassium est ajouté dans un liant à viande utilisé dans les viandes conditionnées ou conservées et dans les sous-produits de viande conditionnés ou conservés, il doit être emballé séparément des épices et condiments |
| (2) Saumure et mélange de salaison à sec employés dans le marinage des viandes conservées et des sous-produits de viande conservés, préparés selon des méthodes de salaison lente (Titre 14) | (2) Si la saumure ou le mélange de salaison à sec est utilisé selon le mode d’emploi donné sur l’étiquette, que le nitrate de potassium soit ajouté seul ou avec du nitrate de sodium, la quantité totale de tels nitrates ainsi ajouté à chaque lot de viande conditionnée ou conservée ou de sous-produits de viande conditionnée ou conservée ne doit pas excéder 0,32 once par 100 livres ou 200 parties par million, calculée avant que le produit ne soit fumé, cuit ou fermenté. Si le nitrate de potassium est ajouté dans la saumure ou le mélange de salaison à sec utilisé dans le marinage des viandes conservées et des sous-produits de viande conservés, il doit être emballé séparément des épices et condiments | ||
| (3) Saucisse séchée; saucisse semi-séchée; viande conservée et sous-produits de viande conservés, préparés selon des méthodes de salaison lente (Titre 14) | (3) Si le nitrate de potassium est ajouté seul ou avec du nitrate de sodium, la quantité totale de tels nitrates ajoutée à chaque lot de saucisse séchée, de saucisse semi-séchée, de viande conditionnée ou conservée, ou de sous-produits de viande conditionnée ou conservée ne doit pas excéder 0,32 once par 100 livres ou 200 parties par million, calculée avant que le produit ne soit fumé, cuit ou fermenté. | ||
| (4) Fromage mûri, ne contenant pas plus de 68 % d’humidité calculée sur la matière non-grasse, et dans la fabrication duquel la fermentation de l’acide lactique et le salage sont complétés plus de 12 heures après la coagulation de la caillebotte par des enzymes alimentaires, et à l’extérieur duquel on applique du sel, soit à l’état sec ou sous forme de saumure | (4) S’il est utilisé seul ou avec du nitrate de sodium, le produit contiendra une quantité maximale de 200 p.p.m. du lait et des produits du lait utilisés. Le résidu dans le fromage fini ne devra pas excéder 50 p.p.m. | ||
| (5) Fromage mûri, moulé et emballé sous vide | (5) S’il est utilisé seul ou avec du nitrate de sodium, le produit contiendra une quantité maximale de 200 p.p.m. du lait et des produits du lait utilisés. Le résidu dans le fromage fini ne devra pas excéder 50 p.p.m. | ||
| S.4 | Nitrate de sodium | (1) Liant à viande pour saucisse séchée; saucisse semi-séchée; viande conservée et sous-produits de viande conservés, préparés selon des méthodes de salaison lente (Titre 14) | (1) Si le liant à viande est utilisé selon le mode d’emploi donné sur l’étiquette, que le nitrate de sodium soit ajouté seul ou avec du nitrate de potassium, la quantité totale de tels nitrates ainsi ajoutée à chaque lot de saucisse séchée, de saucisse semi-séchée, de viande conditionnée ou conservée ou de sous-produits de viande conditionnée ou conservée, ne doit pas excéder 0,32 once par 100 livres ou 200 parties par million, calculée avant que le produit ne soit fumé, cuit ou fermenté. Si le nitrate de potassium est ajouté dans un liant à viande utilisé dans les viandes conditionnée ou conservées et dans les sous-produits de viande conditionnée ou conservés, il doit être emballé séparément des épices et condiments |
| (2) Saumure et mélange de salaison à sec utilisés dans le marinage des viandes conservées et des sous-produits de viande conservés, préparés selon des méthodes de salaison lente (Titre 14) | (2) Si la saumure ou le mélange de salaison à sec est utilisé selon le mode d’emploi donné sur l’étiquette, que le nitrate de sodium soit ajouté seul ou avec du nitrate de potassium, la quantité totale de tels nitrates ainsi ajoutée à chaque lot de viande conditionnée ou conservée ou de sous-produits de viande conditionnée ou conservée ne doit pas excéder 0,32 once par 100 livres ou 200 parties par million, calculée avant que le produit ne soit fumé, cuit ou fermenté. Si le nitrate de potassium est ajouté dans la saumure et le mélange de salaison à sec, utilisés dans le marinage de viande conservée et de sous-produits de viande conservés, il doit être emballé séparément des épices et condiments | ||
| (3) Saucisse séchée; saucisse semi-séchée; viande conservée et sous-produits de viande conservés, préparés selon des méthodes de salaison lente (Titre 14) | (3) Si le nitrate de sodium est ajouté seul ou avec du nitrate de potassium, la quantité totale de tels nitrates ajoutée à chaque lot de saucisse séchée, de saucisse semi-séchée, de viande conditionnée ou conservée ou de sous-produits de viande conditionnée ou conservée ne doit pas excéder 0,32 once par 100 livres ou 200 parties par million, calculée avant que le produit ne soit fumé, cuit ou fermenté. | ||
| (4) Fromage mûri, ne contenant pas plus de 68 % d’humidité calculée sur la matière non-grasse, et dans la fabrication duquel la fermentation de l’acide lactique et le salage sont complétés plus de 12 heures après la coagulation de la caillebotte par des enzymes alimentaires et à l’exception duquel on applique du sel, soit à l’état sec ou sous forme de saumure | (4) S’il est utilisé seul ou avec du nitrate de potassium, le produit contiendra une quantité maximale de 200 p.p.m. du lait et des produits du lait utilisés. Le résidu dans le fromage fini ne devra pas excéder 50 p.p.m. | ||
| (5) Fromage mûri, moulé et emballé sous vide | (5) S’il est utilisé seul ou avec du nitrate de potassium, le produit contiendra une quantité maximale de 200 p.p.m. du lait et des produits du lait. Le résidu dans le fromage fini ne devra pas excéder 50 p.p.m. |
Liste des additifs alimentaires autorisés ayant d’autres utilisations acceptées(Canada)
Non listé
DSL – Liste intérieure des substances (Canada)
Non listé
Liste des Produits chimiques préoccupants, non règlementé
| Produits chimiques préoccupants (réglementés) | |
| Produit chimique | Exemples d’utilisation normale |
| Nitrate de sodium | Engrais, agents de conservation des aliments |
ETATS-UNIS
Liste des substances ajoutées aux aliments Substances Added to Food (formerly EAFUS)
Le nitrate de sodium est un additif alimentaire autorisé pour l’addition directe aux aliments destinés à la consommation humaine, à condition que 1) la quantité de la substance ajoutée aux aliments ne dépasse pas la quantité raisonnablement nécessaire pour accomplir son effet physique, nutritif ou autre effet technique prévu dans les aliments et 2) toute substance destinée à être utilisée dans ou sur les aliments est de qualité alimentaire appropriée et est préparée et manipulée comme un ingrédient alimentaire.
| Substance | SODIUM NITRATE |
| Used for (Technical Effect) | PROPELLANT |
| Document Number (21 CFR) | 172.170 172.175 173.310 175.105 176.180 176.320 181.33 181.34 |
| UNII Code | Active Ingredient | Monograph |
| 8M4L3H2ZVZ | sodium nitrate | menstrual/diuretic |
EUROPE
Listé EINECS(European INventory of Existing Commercial chemical Substances)
Sodium nitrate
EC / List no.: 231-554-3
CAS no.: 7631-99-4
Mol. formula: NNaO3
Hazard classification & labelling
Warning! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye irritation and may intensify fire (oxidiser).
This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 tonnes per annum.
This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
This substance is used in the following products: fertilisers, adhesives and sealants, anti-freeze products, cosmetics and personal care products, hydraulic fluids, washing & cleaning products and heat transfer fluids. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Article service life
Release to the environment of this substance can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release, in processing aids at industrial sites, in the production of articles and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
This substance can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material).
Widespread uses by professional workers
This substance is used in the following products: anti-freeze products, pH regulators and water treatment products, fertilisers, water treatment chemicals, adhesives and sealants, heat transfer fluids and hydraulic fluids.
This substance is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging.
This substance is used for the manufacture of: chemicals.
Other release to the environment of this substance is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).
Formulation or re-packing
This substance is used in the following products: fertilisers, water treatment chemicals, adhesives and sealants, anti-freeze products, explosives, metal surface treatment products, heat transfer fluids, pH regulators and water treatment products and hydraulic fluids. Release to the environment of this substance can occur from industrial use: formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), in the production of articles, as processing aid, in processing aids at industrial sites and of substances in closed systems with minimal release.
Uses at industrial sites
This substance is used in the following products: pH regulators and water treatment products, metal surface treatment products, water treatment chemicals, heat transfer fluids, adhesives and sealants, anti-freeze products, explosives, hydraulic fluids and fertilisers. This substance has an industrial use resulting in manufacture of another substance (use of intermediates). This substance is used in the following areas: formulation of mixtures and/or re-packaging, agriculture, forestry and fishing and scientific research and development. This substance is used for the manufacture of: chemicals. Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, in the production of articles, in processing aids at industrial sites, of substances in closed systems with minimal release and formulation of mixtures.
Manufacture
Release to the environment of this substance can occur from industrial use: manufacturing of the substance.
Flavor and Extract Manufacturers Association (FEMA)
Avantages
Empêche la croissance des microbes.
Source de l’additif
Synthétique
Origine
Il est fabriqué selon différents procédés de synthèse, notamment au départ de l’acide nitrique
| Végétale | Non | Animale | Non | Minérale | Non | Synthétique | Oui |
Convient aux régimes
| Végétarien | Oui | Végétalien | Oui | Hallal | Oui | Kosher | Oui |
| Biologique | Non | Sans gluten | Oui | Sans noix | Oui | Sans œufs | Oui |
Autorisé dans les pays suivants
| Country | Status | Matched Term |
| États-Unis | Approved | Sodium nitrate |
| European Union | Approved | Sodium nitrate |
| Australia and New Zealand | Approved | Sodium nitrate |
| Philippines | Approved | Sodium Nitrate |
| Autriche | Approved | Sodium nitrate |
| Belgique | Approved | Sodium nitrate |
| Bulgarie | Approved | Sodium nitrate |
| Chypre | Approved | Sodium nitrate |
| République tchèque | Approved | Sodium nitrate |
| Danemark | Approved | Sodium nitrate |
| Estonie | Approved | Sodium nitrate |
| Finlande | Approved | Sodium nitrate |
| France | Approved | Sodium nitrate |
| Allemagne | Approved | Sodium nitrate |
| Grèce | Approved | Sodium nitrate |
| Hongrie | Approved | Sodium nitrate |
| Irlande | Approved | Sodium nitrate |
| Italie | Approved | Sodium nitrate |
| Lettonie | Approved | Sodium nitrate |
| Lituanie | Approved | Sodium nitrate |
| Luxembourg | Approved | Sodium nitrate |
| Malte | Approved | Sodium nitrate |
| Pays-Bas | Approved | Sodium nitrate |
| Pologne | Approved | Sodium nitrate |
| Portugal | Approved | Sodium nitrate |
| Roumanie | Approved | Sodium nitrate |
| Slovaquie | Approved | Sodium nitrate |
| Slovénie | Approved | Sodium nitrate |
| Espagne | Approved | Sodium nitrate |
| Suède | Approved | Sodium nitrate |
| Royaume-Uni | Approved | Sodium nitrate |
| Australie | Approved | Sodium nitrate |
| Nouvelle-Zélande | Approved | Sodium nitrate |
Utilisation restreinte
Une quantité maximale peut etre exigé dans certains pays.
Utilisation interdite
Aucuns pays retrouvés
Spécification technique
- CAS 7631-99-4
- Formule moléculaire; NaNO3
- EINECS Number:
Additifs similaires
| Conservateurs | Conservateurs | Conservateurs | Conservateurs |
| E202 | E220 | E250 | E211 |
| Sorbate de potassium | Dioxyde de soufre | Nitrite de sodium | Benzoate de sodium |
Ou peut-on retrouvé
Usage industrielle, domestique, conservateur alimentaire, pharmaceutique et cosmétique.
Exemple de catégories de produits alimentaires transformés contenant l’additif
Fromages
- Viandes transformées non traitées thermiquement
- Autres charcuteries locales traditionnelles
- Bacon
- Filet de bacon
- Wiltshire bacon
- Ham
- rohschincken
Exemple de produit (open food fact)
Autres applications non alimentaires
- Mascara
- Crème hydratante
- Mousse à raser
Cosmétiques et soins de la peau
Ses fonctions (INCI)
- Agent d’hygiène buccale : Fournit des effets cosmétiques à la cavité buccale (nettoyage, désodorisation et protection)
- Agent apaisant : Aide à alléger l’inconfort de la peau ou du cuir chevelu
Cet ingrédient est présent dans 0.09% des cosmétiques.
Example de produit cosmétique en contenant:
| mascara | 8 products |
| facial moisturizer/treatment | 4 products |
| moisturizer | 4 products |
| conditioner | 4 products |
| serums & essences | 3 products |
| shaving cream | 3 products |
| moisturizer with SPF | 2 products |
| hair styling aide | 1 products |
- Tarte Mermaid Skin Hyaluronic H20 Serum
- Honest Beauty Calm & POREfect Serum
- Mizon Joyful Time Essence Mask Rose
- Honest Beauty Beauty Sleep Resurfacing Serum Catrice Glow Booster Serum
- Ivatherm Una Anti-Aging Serum
- L’Oreal Revitalift Anti-Wrinkle Night Cream
- L’Oreal Revitalift Triple Power Anti-Aging Overnight Mask
- Simple Micellar Gel Wash
- Skin Republic Hyaluronic Boost Sheet Mask
- Beyul Moisturizing Mask
- Earth To Skin Super Greens Serum
- PureHeals by Nature Village Propolis 90 Serum
- Talika Bubble Mask Bio-Detox
- WLDKAT Cbd 150Mg Ginger + Kombucha Bubbling Skin Tonic
- Beauty Pro Thermotherapy Warming Gold Foil Mask
- Essence Lash Princess False Lash Mascara
- Hada Labo Shirojyun Premium Whitening Emulsion
- Baby Foot Exfoliation Foot Peel
- Noreva Actipur 3-In-1 Intensive Anti-Imperfection Care
- SEPHORA COLLECTION Detoxifying Foam Cleanser
- Typology Tinted Serum
- Catrice Better Than Waterproof Mascara
- First Aid Beauty Ultra Repair Hydrating Serum
- Laura Geller Quench-N-Tint Hydrating Foundation
- Hema All-In-One Mascara Waterproof
- Maxbrands Face Sheet Mask Avocado Extract
- Redken Extreme Length Sealer Split End Treatment
- Balea Wonderful Repair Übernacht Aufbaufluid
- Farmasi Dr C Tuna Green Vegan Mascara
- Noreva Exfoliac Global 6
- Mario Badescu Super Peptide Serum
- Philosophy Renewed Hope In A Jar Skin Tint
- Matas Striber Fugtmaske
- Skin Republic Hemp Seed Oil Sheet Mask
- Drunk Elephant T.L.C. Framboos™ Glycolic Night Serum
- Drunk Elephant T.L.C. Framboos™ Glycolic Resurfacing Night Serum
- EM Scientific Skincare Antioxidant Facial Serum
- Matas Striber Anti Wrinkle Maske
- Matas Striber Frisk Op Maske
- Peter Thomas Roth Aha/Bha Acne Clearing Gel
- Peter Thomas Roth Cucumber De-Tox Bouncy Hydrating Gel
- Noreva Norelift Chrono-Filler Eye & Lip Anti-Wrinkle Firming Treatment
- cleen beauty Vitamin C Papaya Glow Serum
- Laca Crema Nutritiva
- Philosophy Amazing Grace Body Serum Mousse
- Garnier Miracle Anti-Fatigue Sleeping Cream
- KLAVUU City Defense Treatment Mask
- CHICA Y CHICO Urban Princess Mask – Lifting
- Talika Eye Quintessence
- Laca Crema Con Ceramidas
- Bonjour Mugwort Cream Calming Mask
- Skin Inc. My Daily Dose For Bright Eyes Cream
- La Prairie Anti-Aging Rapid Response Booster
- virtue Exfoliating Scalp Scrub
- virtue Restorative Treatment Mask
Pharmaceutique
- Rince bouche.
- Produit d’hygiène buccale
Autres utilisations
Usages domestiques
- Adhésifs et scellant
- Matériaux de construction / de construction non couverts ailleurs
- Matériaux explosifs
- Produits agricoles (non pesticides)
- Produits de nettoyage et d’entretien de l’ameublement
- Produits de traitement de l’eau
- Produits métalliques non couverts ailleurs
Usages Industrielles
- Adhésifs et produits chimiques d’étanchéité
- Agents de finition Intermédiaires
- Agents de placage et agents de traitement de surface
- Agents odorants
- Agents oxydants / réducteurs
- Aides technologiques, non répertoriées ailleurs
- Ajusteurs de viscosité
- Fabrication d’explosifs
- Matériaux explosifs
- Matériaux explosifs
- Plastifiants
- Produits chimiques agricoles (non pesticides)
- Régulateurs de processus
- Solvants (pour le nettoyage et le dégraissage)
Exemple de produit en contenant
Autres informations
Si toutes les sources de nitrate alimentaire sont prises en compte (additifs, présence naturelle dans les aliments, contaminants environnementaux), les personnes de tous les groupes d’âge présentant une exposition moyenne à élever sont susceptibles de dépasser le niveau de sécurité. Les nitrates peuvent être convertis en nitrite dans la salive. Or, lors de la digestion, les ions nitrites réagissent avec les acides aminés issus des protéines pour former des nitrosamines. 4 de ces substances sont classées cancérogènes probables (avec, en particulier, un risque accru supposé de cancer du côlon). Leur usage intentionnel est donc fortement restreint. Les ions nitrites peuvent également réagir avec le fer pour former du fer nitrosylé, lui aussi promoteur du cancer du côlon. L’Autorité européenne de sécurité alimentaire (Efsa) indique toutefois que les niveaux d’utilisation autorisés sont censés être suffisamment protecteurs. Une consommation élevée de nitrites augmente enfin la méthémoglobinémie, et une vigilance s’impose en particulier chez les enfants forts consommateurs.
Bibliographie
- « Additifs alimentaires, le guide indispensable pour ne plus vous empoisonner » ; Corinne GOUGET, Editions Chariot d’Or, 2013, ISBN 978-2-9118-0669-8. 14e édition de ce best-seller. C. GOUGET s’est fait connaître (et apprécier) tant par son livre que par ses nombreuses apparitions mobilisatrices sur internet (voir notam. youTube).
- « Du poison dans votre assiette ? » ; Cécile Voss, Editions Test-Achats / VSZ, 2000, ISBN 2-930241-18-7.
- « Les additifs alimentaires. Ce que cachent les étiquettes » ; Hélène Barbier Du Vimont, Editions Trédaniel Poche, 2008, ISBN 978-2-84445-860-5.
- 17th report. Toxicological evaluation of some food additives including anticaking agents, antimicrobials, antioxidants, emulsifiers, and thickening agents. Nutrition Meetings Report Series, No. 53, 1974. WHO Technical Reports Series, No. 539, 1974; WHO Food Additives Series N.5.
- AFFSA, 2004. Evaluation des risques liés à l‟utilisation du formaldéhyde en alimentation animale. http://www.econologie.info/share/partager2/1292066952xArJ2J.pdf
- Allergy in Practice, By Johannes Ring, page 110
- Allgen LG, Holmberg G, Persson B, Sörbo B, 1979. Biological fate of methenamine in man. Acta Obstetricia et Gynecologica Scandinavica, 58, 287-293.
- American Industrial Hygiene Association Journal, VOL. 50. NO. 11, (1989). P. 579-585 [AP-O33970]
- AMERICAN JOURNAL OF EPIDEMIOLOGY, VOL. 103, NO. 3, (1976), P. 284-296 [AP-033975]
- AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
- ARZNEIM. FORSCH. DRUG. RES., VOL. 39, NO. 11, (1989), P. 1411-1412 [AP-033983]
- Berglund, F. (1966) Unpublished report BfR (2006). Schulte A, Bernauer U, Madle S, Mielke H, Herbst U, Richter-Reichhelm H-B, Appel KE, Gundert-Remy U. Assessment of the carcinogenicity of formaldehyde [CAS No. 50-00-0]. Bundesinstitut für Risikobewertung.
- Berlin. http://www.bfr.bund.de/cm/238/assessment_of_the_ carcinogenicity_of_formaldehyde.pdf Brendel R, 1964. Studies on rats on the tolerance of hexamethylene tetramine. Arzneimittel-Forsch, 14, 51.
- Bretherick, L., Handbook of reactive chemical hazards. 3rd ed. London; Boston : Butterworth-Heinemann. (1985). [RS-415001]
- Briggs GG, Freeman RK, Yaffe SJ. Drugs in pregnancy and lactation: a reference guide to fetal and neonatal risk. 4th ed. Baltimore: Williams & Wilkins. (1994). Cahill PA, Knight AW, Billinton N, Barker MG, Walsh L, Keenan PO, Williams CV, Tweats DJ, Walmsley RM, 2004. The GreenScreen((R)) genotoxicity assay: a screening validation programme. Mutagenesis, 19(2), 105-119. CICAD (2002).
- Budavari, S. et O’Neil, M., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 11th ed. Rahway ( N.J.) : Merck. (1989). [RM-403001]
- CAMEO Chemicals LICENSE CAMEO Chemicals and all other CAMEO products are available at no charge to those organizations and individuals (recipients) responsible for the safe handling of chemicals. However, some of the chemical data itself is subject to the copyright restrictions of the companies or organizations that provided the data. https://cameochemicals.noaa.gov/help/reference/terms_and_conditions.htm?d_f=false
- Carcinogenesis, VOL.4, NO. 4, (1983), P. 457-459 [AP-033971]
- Centre International de Recherche sur le Cancer (CIRC/OMS) » Monographies
- ChEBI Sodium nitrate http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:63005 ChEBI Ontology http://www.ebi.ac.uk/chebi/userManualForward.do#ChEBI%20Ontology
- ChEMBL Target Tree https://www.ebi.ac.uk/chembl/target/browser
- Chemical Book Inc. – Base de données chimiques et fournisseurs. Les composés chimiques (les additifs en ce qui nous concerne) sont renseignés avec leurs matières premières utilisées ou utilisables (cf. sec° Raw material).
- ChemIDplus Chemical Information Classification https://chem.nlm.nih.gov/chemidplus/
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- ClinicalTrials.gov LICENSE The ClinicalTrials.gov data carry an international copyright outside the United States and its Territories or Possessions. Some ClinicalTrials.gov data may be subject to the copyright of third parties; you should consult these entities for any additional terms of use. https://clinicaltrials.gov/ct2/about-site/terms-conditions#Use https://clinicaltrials.gov/
- Codex Alimentarius
- Comparative Toxicogenomics Database (CTD) LICENSE It is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the MDI Biological Laboratory and NC State University.
- Concise International Chemical Assessment Document 40. Formaldehyde. World Health Organisation. Geneva. CIR, 1992. Final report on the safety assessment of methenamine. Twentieth report of the Cosmetic Ingredient Review expert panel. Journal of the American College of Toxicology 11(4), 531-558. Crebelli R, Falcone E, Aquilina G, Carere A, 1984. In vitro mutagenicity of rubber chemicals and their nitrosation products. Toxicology Letters, 23(3), 307-313.
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
- DailyMed LICENSE https://www.nlm.nih.gov/copyright.html
- Degussa AG, 1985. Unpublished data. Della Porta G, Cabral JR, Parmiani G, 1970. Transplacental Toxicity and Carcinogenesis Studies in Rats Treated with Hexamethylenetetramine. Tumori, 56, 325-334. Della Porta G, Colnaghi MI, Parmiani G, 1968. Non-carcinogenicity of hexamethylenetetramine in mice and rats. Food and Cosmetics Toxicology, 6, 707.
- Demoly P., Portales-Casamar S. CD. ROM Encyclopédique d’Allergologie. Schering-Plough. 2010.
- Dictionnaire pharmaceutique VIDAL » sec° EurêkaSanté (information médicale grand public)
- Dooley JF, Blackburn GR, Schreiner CA, Mackerer CR,1985. Inhibition of the mutagenicity of formaldehyde (HCHO) in the L5178 Y TK+/- mouse lymphoma assay by formaldehyde dehydrogenase (FDH) – Application to characterization of mutagenic components. Environmental Mutagenesis, 7, 9-9. Dumitrescu H, 1975. General analysis of common chemical preservatives. Revista de Igiena, Bacteriologie, Virusologie, Parazitologie, Epidemiologie, Pneumoftiziologie: Igiena, 24(3), 187- 191.
- DOT Emergency Response Guidebook sodium nitrate https://www.phmsa.dot.gov/hazmat/erg/emergency-response-guidebook-erg
- Drevets, C.C. et Seebohm, P.M., «Dermatitis from alcohol.» Journal of Allergy. Vol. 32, no. 4, p. 277-282. (1961). [AP-025612]
- DrugBank LICENSE Creative Common’s Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/legalcode) https://www.drugbank.ca/legal/terms_of_use
- EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- Eckel B, Kirchgessner M and Roth FX, 1992. Zum Einfluss von Ameisensäure auf tägliche Zunahmen, Futteraufnahme, Futterverwertung und Verdaulichkeit 1. Mitteilung Untersuchung zur nutritiven Wirksamkeit von organischen Säuren in der Ferkelaufzucht Journal of Animal Physiology and Animal Nutrition, 67, 93–100.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- EPA Chemical and Products Database (CPDat) LICENSE https://www.epa.gov/privacy/privacy-act-laws-policies-and-resources sodium nitrate https://comptox.epa.gov/dashboard/DTXSID6020937#exposure EPA CPDat Classification https://www.epa.gov/chemical-research/chemical-and-products-database-cpdat
- EPA Chemicals under the TSCA LICENSE https://www.epa.gov/privacy/privacy-act-laws-policies-and-resources Nitric acid sodium salt (1:1) https://www.epa.gov/chemicals-under-tsca
- EPA DSSTox LICENSE https://www.epa.gov/privacy/privacy-act-laws-policies-and-resources Sodium nitrate https://comptox.epa.gov/dashboard/DTXSID6020937 CompTox Chemicals Dashboard Chemical Lists https://comptox.epa.gov/dashboard/chemical_lists/
- EPA Safer Choice LICENSE https://www.epa.gov/privacy/privacy-act-laws-policies-and-resources Sodium nitrate https://www.epa.gov/saferchoice/safer-ingredients EPA Safer Chemical Ingredients Classification https://www.epa.gov/saferchoice
- EU Clinical Trials Register https://www.clinicaltrialsregister.eu/
- European Chemicals Agency (ECHA) LICENSE Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: “Source: European Chemicals Agency, http://echa.europa.eu/”. Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page. https://echa.europa.eu/web/guest/legal-notice Sodium nitrate https://echa.europa.eu/substance-information/-/substanceinfo/100.028.686 Sodium nitrate https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/61079 Sodium Nitrate https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/213018
- European Commission » Health and Consumers » Cosmetics-CosIng
- European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
- Evaluation of certain food additives. Sixty-third report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, no. 928. Geneva, 8-17 June 2004.
- EWG Assessment of Open Scientific Literature
- FAO Nutrition Meetings Report Series, No. 38, 1965. WHO Technical Reports Series, No. 309, 1965; WHO Food Additives Series N.38A. JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1967. 10th report. Specification for the identity and purity and their toxicological evaluation: some emulsifiers and stabilizers and certain other substances.
- FAO Nutrition Meetings Report Series, No. 43, 1967. WHO Technical Reports Series, No. 373, 1967. JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1970. 13th report. Specification for the identity and purity and their toxicological evaluation: some food colours, emulsifiers, stabilizers, anticaking agents, and certain other substances.
- FAO Nutrition Meetings Report Series, No. 46, 1970. WHO Technical Reports Series, No. 445, 1970. JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1972. 15th report. Toxicological evaluation of some enzymes, modified starches and certain other substances.
- FAO Nutrition Meetings Report Series, No. 50, 1972.WHO Technical Reports Series, No. 488, 1972. WHO Food Additives Series N.1. JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1974.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- FDA Center for Food Safety and Applied Nutrition (CFSAN) LICENSE Unless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required. https://www.fda.gov/about-fda/about-website/website-policies#linking
- FDA Center for Food Safety and Applied Nutrition (CFSAN) LICENSE Unless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required. https://www.fda.gov/about-fda/about-website/website-policies#linking SODIUM NITRATE https://www.cfsanappsexternal.fda.gov/scripts/fdcc/index.cfm?set=FoodSubstances&id=SODIUMNITRATE
- FDA Drugs LICENSE Unless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required. https://www.fda.gov/about-fda/about-website/website-policies#linking https://www.fda.gov/Drugs/InformationOnDrugs/ucm129662.htm
- FDA/SPL Indexing Data LICENSE Unless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required. https://www.fda.gov/about-fda/about-website/website-policies#linking 8M4L3H2ZVZ https://www.fda.gov/ForIndustry/DataStandards/SubstanceRegistrationSystem-UniqueIngredientIdentifierUNII/
- Food Additives in Europe, 2000. Status of safety assessment of food additives presently permitted in the EU. TemaNord 2002:560. Tierfarm AG, 1969. Unpublished report. Til HP, Woutersen RA, Feron VJ, Hollanders VHM, Falke HE, Clary JJ, 1989. 2-year drinking-water study of formaldehyde in rats. Food and Chemical Toxicology, 27(2), 77-87.
- Food and Cosmetics Toxicology, 11, 459-462. Hutschenreuter. H. (1956) Z. Lebensmitt. – Untersuch., 104, 161 IARC, 2006. Formaldehyde, 2-butoxyethanol and 1-tert-Butox-2-propanol. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. 88, 2-9. IPCS, 1989. Formaldehyde.
- Food and Cosmetics Toxicology, VOL. 11, (1973), P. 459-462 [AP-033972]
- Food and Cosmetics Toxicology, VOL. 4, (1966), P. 297-320 [AP-033974]
- Food and Cosmetics Toxicology, VOL. 4, (1966), P. 362-363 [AP-O33968]
- Food and Cosmetics Toxicology, VOL. 6, (1968), P. 707-715 [AP-033967]
- Food and Cosmetics Toxicology, VOL. 9, (1971), P. 491-500 [AP-033969]
- Formaldehyde – Global Harmonized System (GHS)
- France. Institut national de recherche et de sécurité, Fiche toxicologique no 177 : Hexaméthylènetétramine. Cahiers de notes documentaires. Paris : INRS. (2011). [RE-005509] http://www.inrs.fr/publications/bdd/fichetox.html
http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_177 - Furness MB, McDonald PJ, Beasley NV, 1974. Urinary antiseptics in asymptomatic bacteriuria of pregnancy. New Zealand Medical Journal, 81, 417-419.
- Ganatra VR, Sawant RM, Chaudhuri NK, Vaidya VN, 1998. Determination of hexamethylene tetramine in the process solution of sol-gel method for nuclear fuel fabrication. Journal of Radioanalytical and Nuclear Chemistry, 230(1-2), 323-326.
- Gandelman A, 1967. Methenamine mandelate: Antimicrobial activity in urine andcorrelation with Formaldehyde levels. Journal of Urology, 97, 533-536. Gelfand, 1963. Respiratory allergy due to chemical compounds encountered in the rubber, lacquer , shellac, and beauty culture industries. Journal of Allergy, 34, 374-381.
- Geneva, World Health Organization (Environmental Health Criteria 89). Re-evaluation of hexamethylene tetramine (E 239) as a food additive EFSA Journal 2014;12(6):3696 36 JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1962. 6th Report. Evaluation of the toxicity of a number of antimicrobials and antioxidants. WHO Technical Reports Series, No. 228, 1962.
- Girmanova I, Chalupa I, Sekerka V, 1991. Genotoxicity of Hexamethylenetetramine. Biologia, 46(11), 1009-1015.
- Gleckman R, Alvarez S, Joubert DW, Matthews SJ, 1979. Drug therapy reviews: methenamine mandelate and methenamine hippurate. American Journal of Hospital Pharmacy, 36, 1509-1512.
- Gollamudi R, Straughn AB, Meyer MC, 1981. Urinary excretion of methenamine andformaldehyde: evaluation of 10 methenamine products in humans. Journal of Pharmaceutical Sciences, 70, 596- 599.
- Goodman, L. S. et Gilman, A., Goodman and Gilman’s : the pharmacological basis of therapeutics. 7th ed. New York : Toronto : Macmillan Pub. Co. ; Collier Macmillan Canada. (1985).
- Greenfield W, Berg R, Moore R, 1969. Determination of urinary formaldehyde following administration of methenamine salts. Clinical Chemistry, 15(12), 1180-5. Haynes WM and Lide DR, 2010. Handbook of chemistry and Physics, 2010-2011, 91st edition. ISBN 978-1-4398-2077-3; pp 3-262 and 16-43. Hurni H and Ohder H, 1973. Reproduction study with formaldehyde hexamethylenetetramine in beagle dogs.
- Hazardous Substances Data Bank (HSDB) SODIUM NITRATE
- Hexamine adsorption study on activated carbon from aqueous solutions for application in treatment of hexamine industrial wastewater. International Journal of Environmental Science and Technology January 2013, 10, 19-26 TemaNord, 2002.
- http://ctdbase.org/about/legal.jsp http://ctdbase.org/detail.go?type=chem&acc=C031618
- http://dardel.info/FoodAdditives.html
- http://morriscookies.co.uk/data/documents/Dangerous-Food-Additives-table.pdf
- http://romseyaustralia.com/additiveban.html
- http://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-additives/detail/en/c/111/
- http://www.foodcanmakeyouill.co.uk/food-additives-and-health-problems.html
- http://www.food-info.net/fr/e/e239.htm
- http://www.food-info.net/uk/e/e251.htm
- http://www.foodlaw.rdg.ac.uk/additive-list.htm
- http://www.naturopathie-holistique.fr/liste-rouge-des-additifs-alimentaires-(danger)-partie-1-15-104.html
- http://www.omedit-normandie.fr/media-files/8866/biosimilaire-ansm.pdf
- http://www.psychomedia.qc.ca/sante/2013-12-04/substances-toxiques-produits-cosmetiques-hygiene
- http://www.ukfoodguide.net/e239.htm
- http://www.ukfoodguide.net/e251.htm
- https://alternative-vegan.com/wp-content/uploads/LM/additifs-GougetLivre.pdf?utm_source=Artcile&utm_medium=Blog&utm_campaign=ExtraitAdd
- https://cosmeticsinfo.org/ingredient/methenamine-0
- https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=J50OIX95QV&searchdb=all&labeltype=all&sortby=rel&audience=professional&page=1&pagesize=200
- https://dermnetnz.org/topics/food-additives-and-e-numbers/
- https://djamel77100.skyrock.com/129260148-Liste-d-ingredients-interdits-pour-les-musulman-e-s.html
- https://docteurtamalou.fr/additifs-alimentaires-plus-dangereux-sante/
- https://druginfo.nlm.nih.gov/drugportal/name/methenamine
- https://drugs.ncats.io/drug/8O0C852CPO
- https://echa.europa.eu/fr/substance-information/-/substanceinfo/100.004.990
- https://echa.europa.eu/fr/substance-information/-/substanceinfo/100.008.058
- https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2014.3898
- https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2014.3696
- https://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:52002PC0662:FR:HTML
- https://forums.futura-sciences.com/chimie/158000-additifs-alilmentaire.html
- https://fr.wikipedia.org/wiki/M%C3%A9th%C3%A9namine
- https://fr.wikipedia.org/wiki/M%C3%A9th%C3%A9namine
- https://incibeauty.com/en/ingredients/21407-methenamine
- https://incibeauty.com/ingredients/738-sodium-nitrate
- https://incibeauty.com/ingredients/738-sodium-nitrate
- https://incidecoder.com/ingredients/sodium-nitrate
- https://noshly.com/additive/e239/preservative/239/#.X1toxGhKguE
- https://noshly.com/additive/e251/colour-fixative-plus/251/#.YE-6TJ1KjSk
- https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-nitrate
- https://pubchem.ncbi.nlm.nih.gov/source/hsdb/726 ChemIDplus
- https://world.openfoodfacts.org/additive/e251-sodium-nitrate/14
- https://world.openfoodfacts.org/additive/en:e239-hexamethylene-tetramine
- https://www.additifs-alimentaires.net/E251.php#:~:text=E251%20%2D%20Nitrate%20de%20sodium%2C%20Salp%C3%AAtre%20du%20Chili&text=Le%20nitrate%20de%20sodium%20est,nitrate%20de%20potassium%20%5B21b%5D.
- https://www.avenir-bio.fr/additif,E251,salpetre-du-chili-nitrate-de-sodium.html
- https://www.bonasavoir.ch/code-e239
- https://www.boulangerienet.fr/bn/bnweb/dt/additif.php
- https://www.canada.ca/fr/environnement-changement-climatique/services/evaluation-substances-existantes/evaluation-prealable-groupe-af-fs.html
- https://www.ceff.info/en/additives/categories?category_id=9&do=categoryDetail
- https://www.cfsanappsexternal.fda.gov/scripts/fdcc/index.cfm?set=FoodSubstances&id=FORMICACID
- https://www.csst.qc.ca/prevention/reptox/Pages/fiche-complete.aspx?no_produit=6320
- https://www.csst.qc.ca/prevention/reptox/Pages/fiche-complete.aspx?no_produit=604#ref_770_1
- https://www.csst.qc.ca/prevention/reptox/Pages/fiche-complete.aspx?no_produit=7807
- https://www.dangersalimentaires.com/en/2011/01/les-additifs-alimentaires/
- https://www.drugbank.ca/
- https://www.echa.europa.eu/documents/10162/24222797/ec_200-579-1_formic_acid_rmoa_concl_8171_en.pdf/745cf276-1065-fa6f-19f3-72c69d16bc84
- https://www.echa.europa.eu/web/guest/information-on-chemicals/ec-inventory?p_p_id=disslists_WAR_disslistsportlet&p_p_lifecycle=1&p_p_state=normal&p_p_mode=view&p_p_col_id=column-1&p_p_col_pos=2&p_p_col_count=3&_disslists_WAR_disslistsportlet_javax.portlet.action=searchDissLists
- https://www.ewg.org/skindeep/ingredients/706140-SODIUM_NITRATE-SODIUM_NITRATE-SODIUM_NITRATE-SODIUM_NITRATE-SODIUM_NITRATE/
- https://www.fda.gov/media/75758/download
- https://www.ferpotravina.cz/seznam-ecek/E239
- https://www.food.gov.uk/business-guidance/approved-additives-and-e-numbers
- https://www.food-detektiv.de/e_nummer_ausgabe.php?id=71&volvox_locale=fr_FR
- https://www.foodnotify.com/en/food-additives/
- https://www.foodpowa.com/additifs-aliments-risque-sante/
- https://www.foodwatch.org/fr/actualites/2019/stop-aux-nitrites-ajoutes-dans-notre-alimentation/
- https://www.fourchette-et-bikini.fr/sante/10-additifs-a-bannir-de-son-alimentation-49049.html
- https://www.frc.ch/toujours-trop-dadditifs/
- https://www.gs1.fi/en/content/view/full/29892
- https://www.guidechem.com/dictionary/fr/544-17-2.html
- https://www.ivyroses.com/Define/E239
- https://www.les-additifs-alimentaires.com/E251-salpetre-du-chili.php
- https://www.nrcan.gc.ca/explosives/resources/brochures/18389?_ga=2.184988129.917457400.1600360371-1857162776.1600360371
- https://www.orthodiet.org/fr/additifs-alimentaires
- https://www.pnrpe.fr/additifs-alimentaires/conservateurs/e251-salpetre-du-chili/?__cf_chl_jschl_tk__=ed808ea3a646b7c7be71b9b7802103959cf7b5e2-1615816841-0-AVoJshJQZmOcW9qT1dZukFftRIkpQAGzFFO26po0iUT8MzJUtI0-CtGbDh9zN5pRixQ9I1z9nxA7cNJdh_BNunVmgDDKfZcLdK9glnJso9b4HW2EORVSQBEv7tWehNJKP72eehEP_QmleOHefZHi2LIwLa372qhGvnP3B5UDyleCq84nHctrgGuJilU4pW4Cj1aZASR7TVNf_PQ73ef0wYTKMKTNTFi0wbjzVF1A8RGhhhs1mgmnxtnpR_Y25dNXdq9Sb0ong_c9gp4_W6Vm_I084AnGboXkIbGAE6A1255XbjFtcmMQ7VgGnMVkzUaoy7v74bPidKLfY6B6FMPc5_0-O0Kyi8R_qekXeRSVAS0DHXYNaBNPzwYG0M9n2g6ZEyemq6bs4z3Lzi9kqwuyi7nbUN0zQO-R35RKMMGSjnd-2aQRuf1LEdgtErMo7fl7UqMzFrnjRXSghmWZaC2dW-I
- https://www.quechoisir.org/comparatif-additifs-alimentaires-n56877/e251-nitrate-de-sodium-p223341/
- https://www.santemagazine.fr/alimentation/additifs-alimentaires/nitrate-de-sodium-e251-170189
- https://www.sudokuwallpapers.com/busqueda.php?number=E239
- https://www.traditionaloven.com/articles/122/dangerous-food-additives-to-avoid
- https://www.tuscany-diet.net/additives/preservatives/
- https://www.vie-publique.fr/en-bref/278164-additifs-alimentaires-dans-la-charcuterie
- IARC (International Agency for Research on Cancer) 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99.
- ILO International Chemical Safety Cards (ICSC) LICENSE The reproduction of ILO material is generally authorized for non-commercial purposes and within established limits. For non-commercial purposes of reproduction of data, any required permission is hereby granted and no further permission must be obtained from the ILO, but acknowledgement to the ILO as the original source must be made. https://www.ilo.org/global/copyright/request-for-permission/lang–en/index.htm
- JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1965. 8th report. Specification for the identity and purity and toxicological evaluation of some antimicrobials and antioxidant.
- JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1998. Safety evaluation of certain food additives and contaminants. Saturated aliphatic acyclic linear primary alcohols, alcohols, aldehydes and acids. WHO Food Additives Series, No 40. Available online: http://www.inchem.org/documents/jecfa/jecmono/v040je10.htm Johnson KA and Johnson DE, 1995. Methane emissions from cattle. Journal of Animal Science, 73, 2483–2492.
- JECFA, 2004. Report of the 27th session of the Codex Committee on food Additives and Contaminant, Geneva, Switzerland, 2004. JECFA, 2005.
- JECFA, 2006. Codex Alimentarius Commission. Report of the 38th session of the Codex Committee on food Additives and Contaminant, Geneva, Switzerland, 2006. De Jong CT, De Klerk A, Beek MT, Veenman C, Van Loveren H, 2007.
- Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Joint FAO/WHO Expert Committee on Food Additives (JECFA) LICENSE Permission from WHO is not required for the use of WHO materials issued under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Intergovernmental Organization (CC BY-NC-SA 3.0 IGO) licence.
- Joint FAO/WHO Expert Committee on Food Additives (JECFA) LICENSE Permission from WHO is not required for the use of WHO materials issued under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Intergovernmental Organization (CC BY-NC-SA 3.0 IGO) licence. https://www.who.int/about/who-we-are/publishing-policies/copyright CHILE SALTPETRE https://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=550
- Kewitz H and Welsch F, 1966. A Yellow Colored Product from Formaldehyde and Kynurenine in Methenamine Treated Rats. Arch. Pharmak. exp. Path, 254, 101-109.
- Kewitz H, 1966. Unpublished report. Klinge E, Männistö P, Mäntylä R, Lamminsivu U, Ottoila P, 1982. Pharmacokinetics of methenamine in healthy volunteers. Journal of Antimicrobial Chemotherapy, 9, 209-216. Kotter L, Terplan G, Schulz H, 1959. Biological detection of preservatives in foods of animal origin. Archiv fuer Lebensmittelhygiene, 10, 145-152.
- Kovac Kralj, A, 2013. Energy-Efficient Hexamine Production Process. Adv. Chem. Eng. Res., Vol. 2 Iss.
- Kovacs AS, Denker P, 1962. Identification and determination of food preservatives in foods. Industrielle Obst- und Gemueseverwertung. 47(1), 1-3.
- Leleu, J., Réactions chimiques dangereuses. Réimp. 1996. Paris : INRS. (1987). www.inrs.fr/dms/inrs/CataloguePapier/ED/TI-ED-697/ed697.pdf
- LICENSE https://www.nlm.nih.gov/copyright.html
- Lijinsky W and Taylor HW, 1977. Feeding tests in rats on mixtures of nitrite with secondary and tertiary-amines of environmental importance. Food and Cosmetics Toxicology, 15(4), 269-274.
- Loeper I and Berzins T. Health effects of selected chemicals 3. Hexamethylenetetraamine. 28, 93-114. 1995 Re-evaluation of hexamethylene tetramine (E 239) as a food additive EFSA Journal 2014;12(6):3696 37 Malorny G and Rietbrock N, 1963.
- Medical Subject Headings (MeSH) MeSH Tree http://www.nlm.nih.gov/mesh/meshhome.html
- Merget R, Topcu M, Friese K, Vormberg R, Fuchs T, Raulf-Heimsoth M, Breitstadt R, 1999. A crosssectional study of workers in the chemical industry with occupational exposure to hexamethylenetetramine. International Archives of Occupational and Environmental Health, 72(8), 533-538.
- MeSH sodium nitrate https://www.ncbi.nlm.nih.gov/mesh/67031618 Carcinogens https://www.ncbi.nlm.nih.gov/mesh/68002273
- Metabolism and excretion of formaldehyde, formic acid and hexamethylenetetramine (used as food preservatives; experiments with radioactively labelled compounds). Thesis, Freie Univ., 82 pp. Selvaag E and Thune P, 1994. Photosensitivity reaction to methenamine hippurate. A case report. Photodermatol Photoimmunol Photomed, 10(6), 259-60. Shimizu H, Suzuki Y, Takemura N, Goto S, Matsushita H, 1985. The results of microbial mutation test for forty-three industrial chemicals.
- Migliore L, Ventura L, Barale R, Loprieno N, Castellino S, Pulci R, 1989. Micronuclei and nuclear anomalies induced in the gastrointestinal epithelium of rats treated with formaldehyde.
- Mutagenesis, 4(5), 327-334. Musher DM, Griffith DP, 1974. Generation of formaldehyde from Methenamine: effect of pH and concentration, and antibacterial effect. Antimicrobial Agents and Chemotherapy, 6, 708-711.
- Natvig H, Andersen J, Rasmussen EW, 1971. A contribution to the toxicological evaluation of hexamethylenetetramine. Food and Cosmetics Toxicology, 9(4), 491-500.
- NCBI;https://www.ncbi.nlm.nih.gov/projects/linkout
- NCI Thesaurus (NCIt) LICENSE Unless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source. https://www.cancer.gov/policies/copyright-reuse Natamycin https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C47634
- New SA, Robins SP, Campbell MK, et al. Dietary influences on bone mass and bone metabolism: further evidence of a positive link between fruit and vegetable consumption and bone health? Am J Clin Nutr 2000; 71:142–51. (article complet disponible via le lien)
- NITE-CMC Sodium nitrate – FY2010 https://www.nite.go.jp/chem/english/ghs/10-mhlw-2022e.html
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- NORMAN Suspect List Exchange NORMAN Suspect List Exchange Classification https://www.norman-network.com/nds/SLE/
- Numéro index 601-042-00-8 dans le tableau 3.1 de l’annexe VI du règlement CE N° 1272/2008 [archive] (16 décembre 2008)
- O’Neil, M.J. et al., The Merck Index : an encyclopedia of chemicals, drugs, & biologicals. 15e éd. Cambridge, G.-B. : Royal Society of Chemistry. (2013). [RM-403001] https://www.rsc.org/Merck-Index/
- OECD (Organisation for Economic Co-operation and Development), 2010. SIDS Initial Assessment Report for SIAM 26. Formic acid and Formates. Paris, France, 15–18 April 2008, 15 pp. Øverland M, Granli T, Kjos NP, Fjetland O, Steien SH and Stokstad M, 2000. Effect of dietary formates on growth performance, carcass traits, sensory quality, intestinal microflora, and stomach alterations in growing-finishing pigs. Journal of Animal Science, 78, 1875–1884.
- Onur F and Acar N, 1992. Simultaneous determination of methylene-blue, hexamethylene tetramine and resorcinol in pharmaceutical formulations by 1st-derivative UV spectrophotometry. International Journal of Pharmaceutics 78(1), 89-91. Orstavik D and Hongslo JK, 1985. Mutagenicity of endodontic sealers. Biomaterials, 6(2), 129-132.
- Oral toxicity of formaldehyde and its derivates, CRC Critical Reviews in Toxicology, 21, 315-328. RTECS, 2005. NIOSH Registry of Toxic Effects of Chemical Substances #MN4725000. http://www.cdc.gov/niosh/ipcsneng/neng1228.html SCF (Scientific Committee on Food), 1977.
- p://www.fao.org/fao-who-codexalimentarius/sh-proxy/zh/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FMeetings%252FCX-711-49%252FCRD%252Ffa49%2BCRD%2B22x.pdf
- Pallauf J and Hüter J, 1993. Studies on the influence of calcium formate on growth, digestibility of crude nutrients, nitrogen balance and calcium retention in weaned piglets, testing facility. Animal Feed Science and Technology, 43, 65–76.
- Pandey CK, Agarwal A, Baronia A, Singh N, 2000. Toxicity of ingested formalin and its management. Human & Experimental Toxicology, 19, 360-366.
- Paseiro Losada P, Simal Lozano J, Simal Gandara J, 1989. Study of the identification of food preservatives. Alimentaria, 204, 57-83.
- PATENTSCOPE (WIPO) SID 394920530 https://pubchem.ncbi.nlm.nih.gov/substance/394920530
- PATENTSCOPE (WIPO), SID 403029884, https://pubchem.ncbi.nlm.nih.gov/substance/403029884
- Patt, Rudolf; Kordsachia, Othar; Süttinger, Richard; Ohtani, Yoshito; Hoesch, Jochen F.; Ehrler, Peter; Eichinger, Rudolf; Holik, Herbert; Hamm (2000). « Paper and Pulp ». Ullmann’s Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH.
- Patt, Rudolf; Kordsachia, Othar; Süttinger, Richard; Ohtani, Yoshito; Hoesch, Jochen F.; Ehrler, Peter; Eichinger, Rudolf; Holik, Herbert; Hamm (2000). « Paper and Pulp ». Ullmann’s Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a18_545
- Patty, F.A., Patty’s industrial hygiene and toxicology. Vol. 2, 3rd ed. New York : John Wiley & Son. (1978).
- Patty, F.A., Patty’s industrial hygiene and toxicology. Vol. 2, 3rd ed. New York : John Wiley & Son. (1978).
- Plog, B.A., Fundamentals of industrial hygiene. Occupational safety and health series, 3rd ed. Chicago, Ill. : National Safety Council. (1988).
- Pohl SA, Caldwell DJ, Lee JT, Coppedge JR, Dunn-Horrocks SL, Stringfellow KD, Jessen K and Farnell MB, 2012. Effects of dietary calcium formate inclusion on broiler performance, skeletal development, and gut maturation. Journal Applied Poultry Research, 21, 311–317.
- Prynne CJ, Mishra GD, O’Connell MA, et al. Fruit and vegetable intakes and bone mineral status: a cross-sectional study in 5 age and sex cohorts. Am J Clin Nutr 2006;83:1420–8. (article complet disponible via le lien)
- PubChem https://pubchem.ncbi.nlm.nih.gov
- PubChem https://pubchem.ncbi.nlm.nih.gov
- Re-evaluation of hexamethylene tetramine (E 239) as a food additive EFSA Journal 2014;12(6):3696 38 Takahashi A and Ono H, 1993. Mutagenicity assessment in 44 epoxy resin hardeners in Salmonella typhimurium tester strains. Chem. Express, 8(9), 785-788. Tanaka T, Kitajima K, Naito T, Hurutani S, Ogura S, 1976. A necropsy case of interstitial nephritis probably related to cefazolin and methenamine. Acta Med Okayama, 30(5), 341-8. Taghdiri M and Zamani, 2013.
- Reports from the Scientific Committee for Food (4th series). Opinion expressed 1977. Food science and techniques, 1977. Schlede E, 1966.
- Restani P and Restelli A, 1992. Formaldehyde and hexamethylenetetramine as food additives: chemical interactions and toxicology. Food Additives & Contaminants, 9(5), 597-605. Restani P, Galli CL, 1991.
- Salmonella mutagenicity tests .5. Results from the testing of 311 chemicals. Environmental and Molecular Mutagenesis, 19, 2-141.
- Sangyo Igaku, 27(6), 400-19. Siffel C and Czeizel AE, 1995. Study of developmental abnormalities and deaths after human zygote exposure. Mutat Res, 334, 293-300. Smolin, EM and Rapoport, L. “The chemistry of heterocyclic compounds, S-Triazines and derivatives.” Interscience publication, New York, 1959
- Sax, N.I., Dangerous properties of industrial materials. 7th ed. Toronto : Van Nostrand Reinhold. (1989). [RR-014005]
- Sodium nitrate – FY2006 https://www.nite.go.jp/chem/english/ghs/06-imcg-1384e.html
- SODIUM NITRATE https://cameochemicals.noaa.gov/chemical/1509 CAMEO Chemical Reactivity Classification https://cameochemicals.noaa.gov/browse/react
- Sodium nitrate https://chem.nlm.nih.gov/chemidplus/sid/0007631994
- Sodium nitrate https://www.drugbank.ca/drugs/DB15952
- SODIUM NITRATE https://www.ilo.org/dyn/icsc/showcard.display?p_version=2&p_card_id=0185
- SpectraBase SODIUM NITRATE https://spectrabase.com/spectrum/KENfrBY8gE SODIUM NITRATE https://spectrabase.com/spectrum/6BAcX6KRAZl SODIUM-NITRATE https://spectrabase.com/spectrum/GNXmqAUrFgU NITRIC ACID, SODIUM SALT https://spectrabase.com/spectrum/KzY5JeR2c7A SODIUM NITRATE https://spectrabase.com/spectrum/3R2aswkfY8L SODA NITER – SODIUM NITRATE (TARAPACA, CHILE) https://spectrabase.com/spectrum/E3unGMsqAOn Sodium nitrate https://spectrabase.com/spectrum/3HiJTUdVvPd
- Springer Nature
- Strom JG, Jun HW, 1993. Effect of urine pH and ascorbic acid on the rate of conversion of methenamine to formaldehyde. Biopharmaceutics & Drug Disposition, 14, 61-69.
- The Chernoff-Kavlock assay: Its validation and application in rats. Teratogenesis, Carcinogenesis, and Mutagenesis, 7, 73-83. Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, 1992.
- The National Institute for Occupational Safety and Health (NIOSH) LICENSE The information provided using CDC Web site is only intended to be general summary information to the public. It is not intended to take the place of either the written law or regulations. https://www.cdc.gov/Other/disclaimer.html Sodium(I) nitrate (1:1) https://www.cdc.gov/niosh-rtecs/WC557300.html
- Thieme Chemistry LICENSE The Thieme Chemistry contribution within PubChem is provided under a CC-BY-NC-ND 4.0 license, unless otherwise stated. https://creativecommons.org/licenses/by-nc-nd/4.0/
- TUMORI, VOL. 56, (1970), P. 325-334 [AP-033973]
- UN Globally Harmonized System of Classification and Labelling of Chemicals (GHS) GHS Classification Tree http://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html
- Unpublished report. Meissner, F, Schwiedessen, E. and Othmer, D.F. Shatyski ODF, (1954). Continuous production of hexamethylenetetramine. Ind. Eng. Chem. 46, 724.
- Verschueren, K., Handbook of environmental data on organic chemicals. 2nd ed.. New York : Van Nostrand Reinhold Co.. (c1983).
- Vortrag auf der X. Tagung des Ernährungswissenschaftlichen Beirats der deutschen Fischwirtschaft, Bremen. Malorny G, 1966.
- Vujosevic, M., Zivkovic, S., Fister, S. (1986): In vivo mammalian bone marrow cytogenetic test (chromosomal analysis) – Result of testing UROTOVETR. Acta Vet (Beograd), 36, 91-94 WHO, 2008. Guidelines for drinking-water quality. Third Edition, .incorporating first and second addenda. World Health Organisation. Geneva. p. 377b. Available at: http://www.who.int/water_sanitation_health/dwq/fulltext.pdf?ua=1 Wickramaratne GAS, 1987.
- Wikipedia sodium nitrate https://en.wikipedia.org/wiki/Sodium_nitrate
- Wiley https://pubchem.ncbi.nlm.nih.gov/substance/?source=wiley&sourceid=14196
- www.additifs-alimentaires.net